Neurotoxins and Their Pharmacological Implications
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Neurotoxins and Their Pharmacological Implications A Biological Council Symposium by Peter Jenner

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Published by Raven Pr .
Written in English


  • Neurology & clinical neurophysiology,
  • Molecular pharmacology,
  • Toxins,
  • Neurochemistry,
  • Neuropsychopharmacology,
  • Congresses,
  • Neurotoxic agents,
  • Physiological effect

Book details:

The Physical Object
Number of Pages297
ID Numbers
Open LibraryOL8174635M
ISBN 100881673358
ISBN 109780881673357

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Appears in 32 books from Page - Anatomy, pigmentation, ventral and dorsal subpopulations of the substantia nigra, and differential cell death in Parkinson's disease, J. Neurol. Appears in 23 books from It is easy to anticipate that additional pathologic conditions might be treated with botulinum neurotoxins following the development of three lines of research: 1) definition of the molecular, cellular, tissue, and pharmacological properties of the many novel botulinum toxins that are being discovered; 2) molecular design and biotechnology production of botulinum neurotoxins endowed with novel Cited by: Neurotoxins and Neurodevelopment. The leading cause of neonatal mortality is birth defects, in some cases the result of exposure to neurotoxins. Even when not resulting in death, damage to the developing brain or central nervous system as a result of exposure can result in negative impacts .   Mercury is a neurotoxin, meaning it has detrimental effects on the nervous system. It can damage the brain and lead to physical and emotional disorders. So whether its presence is natural or anthropogenic, it’s a potential problem for humans. How big a problem depends on the form of the mercury, how much is present.

The nerve terminal intoxication by botulinum neurotoxins is a multi-step process. The first step (1) is the binding of the HC domain (green) to a polysialoganglioside (PSG) receptor of the presynaptic membrane (gray and black), followed by binding to a protein by: COVID Resources. Reliable information about the coronavirus (COVID) is available from the World Health Organization (current situation, international travel).Numerous and frequently-updated resource results are available from this ’s WebJunction has pulled together information and resources to assist library staff as they consider how to handle coronavirus. Mechanisms of Neurotoxin Action. Neurotoxins tend to impede vital cytoplasmic processes, and this can be accomplished by an action at one of many different sites. Identified neurotoxins are known to (1) disrupt energy production, (2) dysregulate ionic gradients, (3) impair neurotransmitter synthesis/storage/release, (4) interfere with transcription, translation, and formation of requisite . Neurotoxin, substance that alters the structure or function of the nervous system. More than 1, chemicals are known to have neurotoxic effects in animals. The substances include a wide range of natural and human-made chemical compounds, from snake venom and pesticides to ethyl alcohol, heroin, and cocaine.